Ago2 or Dicer knockdown effects on mRNA levels in HeLa

ABSTRACT: Analysis of mRNA changes in HeLa cells following Ago2 or Dicer depletion. Dicer, a cytoplasmic RNase III, generates the mature form of small RNAs including microRNA. Ago2 is a component of an effector complex of microRNA. Keywords: gene expression array-based (RNA / in situ oligonucleotide) siRNA against Ago2 or Dicer were trasnfected into HeLa cells. siRNA against GFP was used as a control. Biologically duplicated total RNAs were prepared from HeLa cells, 24 hrs and 48 hrs after siRNA transfection.

ORGANISM(S): Homo sapiens

SUBMITTER: Jinju Han 

PROVIDER: E-GEOD-13638 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress