Salmon Spawning Migration: Metabolic Shifts and Environmental Triggers

ABSTRACT: A large-scale functional genomics study revealed shifting energy generating processes in white muscle during the final 1,300 km migration of wild sockeye salmon to their spawning grounds in the Fraser River, British Columbia. In 2006, Lower Adams stock sockeye salmon ceased feeding after passing the Queen Charlotte Islands, 850 km from the Fraser River. Enhanced protein turnover and reduced transcription of actin, muscle contractile and heme-related proteins were early starvation responses in saltwater. Arrival to the estuarine environment triggered massive protein turnover through induction of proteasoma and lysosomal proteolysis and protein biosynthesis, and a shift from anaerobic glycolysis to oxidative phosphorylation. Response to entry into freshwater was modest, with up-regulati

ORGANISM(S): Oncorhynchus nerka

SUBMITTER: David Patterson 

PROVIDER: E-GEOD-13657 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress