Comparative transcriptome and phenotype analysis of acid-stressed Bacillus cereus strain ATCC 14579

ABSTRACT: The food-borne human pathogen Bacillus cereus is found in environments that often have a low pH, such as food and soil. The physiological response upon exposure to several levels of acidity were investigated of B. cereus model strain ATCC 14579, to elucidate the response of B. cereus to acid stress. pH 5.4, pH 5.0, pH 4.8 and pH 4.5 were selected to conduct microarray analyses, based on the differences in physiological response upon exposure to the acid conditions. The transcriptome data revealed response specific profiles. Showing mechanisms induced upon all the different acid down-shocks, such as nitrate reductase and energy production genes, and several genes specifically expressed differentially in mild or lethal levels of acidity, such as F1F0-ATPase and cydAB. Furthermore, mechanisms

ORGANISM(S): Bacillus cereus

SUBMITTER: Richard van Kranenburg 

PROVIDER: E-GEOD-13711 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress