Goat mammary gland differentiation during pregnancy

ABSTRACT: Development of mammary secretory epithelium and its functional differentiation occur during pregnancy under combined actions of ovarian steroids, pituitary hormones and growth factors. If the effect of these molecules is relatively well known, effect of differentiation factors expressed locally is not enough characterized. To understand local regulation of mammary tissue development and differentiation we realized transcriptional analysis on 5 physiological stages (4 during pregnancy and 1 during lactation). An appropriate experimental design was drawn to follow gene expression profiles during differentiation of mammary tissue. Results showed that at mid-pregnancy, mammary tissue was enough defferentiated into secretory epithelium to express milk protein genes and genes of the immune respo

ORGANISM(S): Capra hircus

SUBMITTER: Patrice Martin 

PROVIDER: E-GEOD-14008 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress