Transcription profiling of human developing lung

ABSTRACT: We decompose the genome-wide expression patterns in 38 embryonic human lung (53-154 days post conception/dpc) into their independent, dominant directions of transcriptomic sample variation in order togain global insight of the developing human lung transcriptome.The characteristic genes and their corresponding bio–ontologic attribute profile for the latter were identified. We noted the over–representation of lung specific attributes (e.g., surfactant proteins) traditionally associated with later developmental stages, and highly ranked attributes (e.g., chemokine–immunologic processes) not previously reported nor immediately apparent in an early lung development context. We defined the 3,223–gene union of the characteristic genes of the 3 most dominant sources of variation as the de

ORGANISM(S): Homo sapiens

SUBMITTER: Alvin Kho 

PROVIDER: E-GEOD-14334 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress