Expression data from mouse model of Ecoli mastitis

ABSTRACT: We performed a genome-wide transcriptional analysis in the mammary gland in a mouse model of E. coli mastitis using high-density mouse oligonucleotide microarrays. This global transcription analysis revealed that about 7% of tested genes are mobilized in the mouse mammary gland to E. coli endotoxin. We identified 1402 differentially expressed genes that were associated with physiological system development/function and molecular/cellular functions and metabolic/signalling pathways that are highly relevant to host immune-inflammatory defense response against E. coli infection. The mouse differentially expressed genes through the use of comparative mapping/genomics and positional information on reported QTL for bovine mastitis allowed identifying 293 potential candidate genes for bovine mast

ORGANISM(S): Mus musculus

SUBMITTER: Roger Vallejo 

PROVIDER: E-GEOD-14485 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress