Comparison of glioblastoma tissue, glioblastoma primary culture, and normal brain
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Biaoyang Lin
PROVIDER: E-GEOD-14878 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Massively parallel signature sequencing and bioinformatics analysis identifies up-regulation of TGFBI and SOX4 in human glioblastoma.
Lin Biaoyang B Madan Anup A Yoon Jae-Geun JG Fang Xuefeng X Yan Xiaowei X Kim Taek-Kyun TK Hwang Daehee D Hood Leroy L Foltz Gregory G
PloS one 20100419 4
<h4>Background</h4>A comprehensive network-based understanding of molecular pathways abnormally altered in glioblastoma multiforme (GBM) is essential for developing effective therapeutic approaches for this deadly disease.<h4>Methodology/principal findings</h4>Applying a next generation sequencing technology, massively parallel signature sequencing (MPSS), we identified a total of 4535 genes that are differentially expressed between normal brain and GBM tissue. The expression changes of three up ...[more]
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