Investigation of colominic acid effects on immortalized Schwann cells

ABSTRACT: The purpose of the present study is to influence of CA coating on immortalized Schwann cells in vitro in comparison to standard culture conditions as well as to laminin as a positive standard. CA is a homopolymer of polysialic acid (PSA), which has – attached to the neuronal cell adhesion molecule (NCAM) – emerged as particulate attractive candidate for promoting morphological plasticity of axonal processes during axonal path finding and activity-dependent remodelling. For this purpose self-spotted microarrays with 352 neurospecific genes were hybridized with mRNA from immortalized Schwann cells cultivated on different coating conditions: In order to enable a comprehensive comparison to the established coating material laminin as well as to standard coating conditions (cultivation on

ORGANISM(S): Rattus norvegicus

SUBMITTER: Cornelia Repenning 

PROVIDER: E-GEOD-14944 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress