Expression data from human embryonic (9-12w) and post-natal livers

ABSTRACT: The liver is a multifunctional organ, which undergoes rapid changes during the developmental period and relies on tightly-regulated gene expression. Little is known regarding the complex expression patterns of mRNAs during the early stages of human liver development in comparison to post-natal livers. We used microarrays to detail the global programme of gene expression during liver development following specification, at the stage of proliferation and differentiation when compared to post-natal livers, and identified distinct classes of up-regulated and downregulated genes during this process. Liver tissues of aborted human embryos (9-12 weeks from last period) and adult patients (1.5, 42 and 81 years) were obtained under an IRB approval for RNA extraction and hybridization on Affymetrix

ORGANISM(S): Homo sapiens

SUBMITTER: Galit Tzur 

PROVIDER: E-GEOD-15238 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress