Systems epidemiology of blood transcriptome variability in a representative sample of postmenopausal women

ABSTRACT: Using a large representative sample of postmenopausal women in the Norwegian Women and Cancer (NOWAC) postgenome study, we investigated blood gene expression changes due to intra-technical variability, normal inter-individuality (age, body mass index, fasting status), and exposure variables (smoking, hormone therapy and medication use) at proportion and level of real life situation revealing mechanistic insights of these effects mirrored in blood. We used a representative sample of postmenopausal women (N=286) in the NOWAC postgenome study. We investigated blood gene expression changes due to intra-technical variability, normal inter-individuality (age, body mass index, fasting status), and exposure variables (smoking, hormone therapy and medication use). A total of 304 arrays, including 1

ORGANISM(S): Homo sapiens

SUBMITTER: Vanessa Dumeaux 

PROVIDER: E-GEOD-15289 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress