Resistance of primary ovarian cancer cells to oncolytic adenoviruses part1 of 2

ABSTRACT: The mechanisms of primary ovarian cancer cells for resistance to viral oncolysis were investigated using Ad5/35.IR.E1A/TRAIL on clonal cultures derived from ovc316m cells. Part 1 of 2, initital study involving 5 clonal ovc316m cultures Cells were infected for 8 days and cell survival determined by MTT assay. Uninfected control cells of each clonal culture were utilized for DNA expression arrays. SKOV3-ip1 cells were used for reference RNA in all samples.

ORGANISM(S): Homo sapiens

SUBMITTER: Ying Liu 

PROVIDER: E-GEOD-15350 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress