Gene expression changes in PBMCs from metabolic syndrome patients after acute intake of phenol-rich virgin olive oil

ABSTRACT: Some studies have shown that acute intake of high-phenol virgin olive oil reduces pro-inflammatory, pro-oxidant and pro-thrombotic states, but nowadays still remains unclear if those effects attributed to its phenolic fraction could be exerted at transcriptional level in vivo. Two virgin olive oil-based breakfasts with high (398 ppm) and low (70 ppm) content of phenolic compounds were administered to twenty patients (9 men and 11 women) with metabolic syndrome following a double-blinded random crossover design. Prior to the first breakfast intervention, participants followed a 6-week washout period in which they were instructed to not take vitamins, soy supplements, or any drug. To eliminate the potential effect that might exist in their usual dietary habits, all subjects followed a low-fa

ORGANISM(S): Homo sapiens

SUBMITTER: Juan Ruano 

PROVIDER: E-GEOD-15812 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress