The PhyR-sigmaEcfG signaling cascade is involved in stress response and symbiotic efficiency in Bradyrhizobium japonicum

ABSTRACT: PhyR is an unusual type of response regulator consisting of a receiver domain and an extracytoplasmic function (ECF) sigma factor-like domain. It was recently described as a master regulator of general stress response in Methylobacterium extorquens. Orthologues of this regulator are present in essentially all free-living Alphaproteobacteria. In most of them, phyR is genetically closely linked to a gene encoding an ECF sigma factor. Here, we investigate the role of these two regulators in the soybean symbiont Bradyrhizobium japonicum USDA110. Using deletion mutants and phenotypic assays, we showed that PhyR and the ECF sigma factor sigma(EcfG) are involved in heat shock and desiccation resistance upon carbon starvation. Both mutants had symbiotic defects on the plant hosts Glycine max (soyb

ORGANISM(S): Bradyrhizobium japonicum

SUBMITTER: Hans-Martin Fischer 

PROVIDER: E-GEOD-15910 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress