Actinobacillus pleuropneumoniae during a natural infection in pigs

ABSTRACT: Actinobacillus pleuropneumoniae is the etiological agent of porcine pleuropneumonia, a respiratory disease which causes great economic losses worldwide. Many virulence factors are involved in the pathogenesis, namely capsular polysaccharides, RTX toxins, LPS and many iron acquisition systems. In order to identify genes that are expressed in vivo during a natural infection, we undertook transcript profiling experiments with an A. pleuropneumoniae DNA microarray, after recovery of bacterial mRNAs from serotype 5b-infected porcine lungs. Comparative Genomic Hybridizations between Actinobacillus pleuropneumoniae serotype 5b strain L20 (ref) and serotype 5b fresh field isolate 896-07, recovered from infected pig lung tissues following natural acute infection. Two condition transcript profiling

ORGANISM(S): Actinobacillus pleuropneumoniae

SUBMITTER: Martine Denicourt 

PROVIDER: E-GEOD-15911 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress