RNAi profiling of Drosophila after Nipped-B and Rad21 sister chromatid cohesin proteins in Drosophila ML-DmBG3 cells

ABSTRACT: Effects of Nipped-B and Rad21 sister chromatid cohesin proteins on gene expression data in ML-DmBG3 cells derived from Drosophila melanogaster larval central nervous system; We examined the effects of Nipped-B and Rad21 knockdown on gene expression in BG3 cells using microarrays that measure over 18,700 transcripts to (a) determine if the effects of cohesion on E(spl)-C and invected-engrailed expression are unique, (b) look for effects of cohesin on regulators of E(spl)-C and engrailed, and (c) obtain a comprehensive view of the effects of cohesin on gene expression. Experiment Overall Design: Effects of cohesin knockdown on E(spl)-C and invected-engrailed transcription vary over time, so we used two independent samples for three days after RNAi treatment, one four day and one six day samp

ORGANISM(S): Drosophila melanogaster

SUBMITTER: Akbar Siddiqui 

PROVIDER: E-GEOD-16152 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress