Toxicogenomic response of Rhodospirillum rubrum S1H to the model micropollutant triclosan

ABSTRACT: Aiming at the development of a micropollutant biosensor in the frame of the Micro-Ecological Life Support System Alternative (MELiSSA), a pilot study was initiated to identify triclosan (TCS)-responsive biomarker genes in the MELiSSA carbon-mineralizing microorganism, Rhodospirillum rubrum S1H. TCS is a biocide, commonly found in human excrements and is considered an emerging pollutant in wastewater and the environment. Chronic exposure to MELiSSA-relevant concentrations (≥25 µg L-1) TCS caused a significant extension of the lag phase without affecting the growth rate. Analytical determination gave no indication of TCS biodegradation during the growth experiment and flow cytometric viability analyses revealed that TCS is only slightly toxic to R. rubrum. Through microarray analyses, the ge

ORGANISM(S): Rhodospirillum rubrum

SUBMITTER: Pieter Monsieurs 

PROVIDER: E-GEOD-16189 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress