Transcription profiling of Sachharomyces cerevisiae cultures following L-carnitine supplementation

ABSTRACT: Microarray analysis of the effect of L-carnitine supplementation on global expression of Sachharomyces cerevisiae cultures in logarithmic growing conditions and after exposure to H2O2 induced oxidative stress; L-Carnitine plays a well documented role in eukaryotic energy homeostasis by acting as a shuttling molecule for activated acyl residues across intracellular membranes. This activity is supported by carnitine acyl-transferases and transporters, and is referred to as the carnitine shuttle. However, several pleiotropic and often beneficial effects of carnitine in humans have been reported that appear to be unrelated to the shuttling activity, but little conclusive evidence regarding the molecular networks that would be affected by carnitine exist. We have recently demonstrated a protect

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Jaco Franken 

PROVIDER: E-GEOD-16346 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress