Detection of Cancer with Serum miRNAs on an Oligonucleotide Microarray

ABSTRACT: Micro RNAs (miRNAs) are a class of small, non-coding RNA species that play critical roles throughout cellular development and regulation. miRNA expression patterns taken from various tissue types often point to the cellular lineage of an individual tissue Arrays for serum miRNA analysis were constructed with 547 human miRNA sequences obtained from the Sanger Database version 10.0 which appeared on 8/2/07. Because of limited space on the array, the probe list was modified to exclude a few newer miRNAs that had recently been added. The array includes miRNA probes for all studies referenced by this paper. Three probes were written for each miRNA: an anti-sensed wild-type version, a double-mutant control probe, and a sense control version. Antisense controls were not included if the correspon

ORGANISM(S): Homo sapiens

SUBMITTER: Brooke Anderson 

PROVIDER: E-GEOD-16512 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress