Response of Pseudomonas aeruginosa PAO1 to low shear modeled microgravity

ABSTRACT: Anticipating the risk for infectious disease during space exploration and habitation is a critical factor to ensure safety, health and performance of the crewmembers. As a ubiquitous environmental organism that is occasionally part of the human flora, Pseudomonas aeruginosa could pose a health hazard for the immuno-compromised astronauts. In order to gain insights in the behavior of P. aeruginosa in spaceflight conditions, two spaceflight-analogue culture systems, i.e. the rotating wall vessel (RWV) and the random position machine (RPM), were used. Microarray analysis of P. aeruginosa PAO1 grown in the low shear modeled microgravity (LSMMG) environment of the RWV compared to the normal gravity control (NG), revealed a regulatory role for AlgU (RpoE). Specifically, P. aeruginosa cultured in

ORGANISM(S): Pseudomonas aeruginosa PAO1

SUBMITTER: Cheryl Nickerson 

PROVIDER: E-GEOD-16970 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress