Cold-induced silencing mediated by long antisense FLC transcripts

ABSTRACT: Hight throughput techniques have revealed huge complexity in antisense RNAs in many organisms. We have explored the complexity of this class of transcripts and functional links to Polycomb silencing thought analysis of non-coding RNAs of Arabidopsis FLC. FLC is repressed and epigenetically silenced by prolonged cold, enabling plants to undergo the floral transition. Single nucleotide resolution tiling array revealed long non-coding transcripts covering the entire FLC locus. The most abundant of these are capped and polyadenylated, initiate over a 100 nucleotide window just downstream of the sense polyA site, are differentially spliced and terminate either within the sense gene or its promoter. Their levels correlate with FLC sense transcripts in all mutants and conditions tested except col

ORGANISM(S): Arabidopsis thaliana

SUBMITTER: Rene Dreos 

PROVIDER: E-GEOD-16977 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress