Epithelial cells in contact with bacterial supernatant
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Chimene Moreilhon
PROVIDER: E-GEOD-1704 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Live Staphylococcus aureus and bacterial soluble factors induce different transcriptional responses in human airway cells.
Moreilhon Chimène C Gras Delphine D Hologne Coralie C Bajolet Odile O Cottrez Françoise F Magnone Virginie V Merten Marc M Groux Hervé H Puchelle Edith E Barbry Pascal P
Physiological genomics 20041214 3
To characterize the response of respiratory epithelium to infection by Staphylococcus aureus (S. aureus), human airway cells were incubated for 1 to 24 h with a supernatant of a S. aureus culture (bacterial supernatant), then profiled with a pangenomic DNA microarray. Because an upregulation of many genes was noticed around 3 h, three independent approaches were then used to characterize the host response to a 3-h contact either with bacterial supernatant or with live bacteria: 1) a DNA microarr ...[more]
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