Identification of direct transcriptional targets of V600EBRAF/MEK in melanoma

ABSTRACT: A375P melanoma cells were treated with 1uM of the MEK inhibitor PD184352 or 0.4uM of the V600EBRAF inhibitor PLX4720 for 2hr, 6hr and 24hrs. DMSO treatment for 2hr, 6hr and 24hrs serves as the negative control Triplicate experiments were performed for DMSO, PD184352 and PLX4720 treatment at 3 timepoints - 2, 6, 24hrs.

ORGANISM(S): Homo sapiens

SUBMITTER: Richard Marais 

PROVIDER: E-GEOD-17089 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress