Gene expression in rat kidney following recovery from acute renal failure (ARF)

ABSTRACT: This experiment was designed to study the alteration in expression of mRNA is kidney following recovery from transient acute renal failure. The model used was a 52 min. bilateral renal artery clamping, followed by reperfusion, which resulted in a transient loss of renal function, followed by a functional recovery. All tissue in this study was harvested 35 days post-surgery, when renal function was restored, and renal structure largelyy normal. For controls, sham-operated animals were used. An N of 6 post-ischemia reperfusion animals were used with 6 sham-operated controls. For hybridization studies, RNA from one of six post-ischemic acute renal failure animals were compared with with RNA from kidney of six sham-operated control animals. Each ARF vs. sham-operated comparison was perfo

ORGANISM(S): Rattus norvegicus

SUBMITTER: David Basile 

PROVIDER: E-GEOD-1714 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress