Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Veronique Bourdon
PROVIDER: E-GEOD-1715 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Narayan Gopeshwar G Bourdon Veronique V Chaganti Seeta S Arias-Pulido Hugo H Nandula Subhadra V SV Rao Pulivarthi H PH Gissmann Lutz L Dürst Matthias M Schneider Achim A Pothuri Bhavana B Mansukhani Mahesh M Basso Katia K Chaganti R S K RS Murty Vundavalli V VV
Genes, chromosomes & cancer 20070401 4
Cervical cancer (CC) cells exhibit complex karyotypic alterations, which is consistent with deregulation of numerous critical genes in its formation and progression. To characterize this karyotypic complexity at the molecular level, we used cDNA array comparative genomic hybridization (aCGH) to analyze 29 CC cases and identified a number of over represented and deleted genes. The aCGH analysis revealed at least 17 recurrent amplicons and six common regions of deletions. These regions contain sev ...[more]