Inflammatory gene expression in response to Francisella tularensis exposure in Balb/c mice

ABSTRACT: Francisella tularensis may enter the body thorugh the lungs and cause fatal infection. In this study the inflammatory response to the virulent strain of Francisella (Schu4) was mapped over a 96h time-course using a custom microarray. Six groups of 4 mice were exposed to aerosolised Francisella tularensis and a three groups exposed to vehicle only control (media only). Following exposure mice were culled at 4 timepoints (1, 24, 48 and 96h). RNA was extracted and run on the custom array.

ORGANISM(S): Mus musculus

SUBMITTER: Jonathan David 

PROVIDER: E-GEOD-17248 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress