Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Kc167 ORC2 Localization

ABSTRACT: modENCODE_submission_674 This submission comes from a modENCODE project of David MacAlpine. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We will precisely identify sequence elements that direct DNA replication by using chromatin immunoprecipitation of known replication initiation complexes. These experiments will be conducted in multiple cell types and developmental tissues. Keywords: CHIP-chip For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODEDataReleasePolicyFinal2008.pdf EXPERIMENT TYPE: CHIP-chip. BIOLOGICAL SOURCE: Cell Line: Kc167; Tissue: embryo-derived cell-line; Genotype: se/e; Sex: Female NUMBER OF REPLICATES: 2; EXPERIMENTAL FACTORS: Antibody dORC2

ORGANISM(S): Drosophila melanogaster

SUBMITTER: David MacAlpine 

PROVIDER: E-GEOD-17282 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Json Xml
altmetric image

Publications

Drosophila ORC localizes to open chromatin and marks sites of cohesin complex loading.

MacAlpine Heather K HK   Gordân Raluca R   Powell Sara K SK   Hartemink Alexander J AJ   MacAlpine David M DM  

Genome research 20091207 2

The origin recognition complex (ORC) is an essential DNA replication initiation factor conserved in all eukaryotes. In Saccharomyces cerevisiae, ORC binds to specific DNA elements; however, in higher eukaryotes, ORC exhibits little sequence specificity in vitro or in vivo. We investigated the genome-wide distribution of ORC in Drosophila and found that ORC localizes to specific chromosomal locations in the absence of any discernible simple motif. Although no clear sequence motif emerged, we were  ...[more]

Similar Datasets

Transcriptomics Kc167 ORC Localization in hydroxyurea (HU)
2014-12-05 | E-GEOD-63914 | biostudies-arrayexpress
Transcriptomics TAP-ORC2 and control ChIP experiments in Drosophila Kc167 cells
2010-06-20 | E-GEOD-18942 | biostudies-arrayexpress
Transcriptomics Kc167 Mcm2-7 Localization in HU
2014-11-27 | E-GEOD-63680 | biostudies-arrayexpress
Transcriptomics Kc167 MCM Localization
2010-05-15 | E-GEOD-17283 | biostudies-arrayexpress
Transcriptomics Kc167 Replication Timing
2009-07-29 | E-GEOD-17279 | biostudies-arrayexpress
Transcriptomics ML-DmBG3-c2 Replication Timing
2009-07-29 | E-GEOD-17281 | biostudies-arrayexpress
Transcriptomics S2-DSRC Replication Timing
2010-05-15 | E-GEOD-17280 | biostudies-arrayexpress
Transcriptomics S2-DRSC Replication Origins
2010-05-15 | E-GEOD-17286 | biostudies-arrayexpress
Transcriptomics Kc167 Replication Origins
2010-05-15 | E-GEOD-17285 | biostudies-arrayexpress
Genomics Early Origins Meta-peak generation
2011-03-16 | E-GEOD-27981 | biostudies-arrayexpress