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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of preimplantation mouse embryo development

ABSTRACT: Preimplantation mouse embryo development study on Affymetrix MOE430A. Zeng et al (2004) Dev Biol 272:483-496.

ORGANISM(S): Mus musculus

SUBMITTER: Richard Schultz

PROVIDER: E-GEOD-1744 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Transcript profiling during preimplantation mouse development.

Zeng Fanyi F Baldwin Don A DA Schultz Richard M RM

Developmental biology 20040801 2

Studies using low-resolution methods to assess gene expression during preimplantation mouse development indicate that changes in gene expression either precede or occur concomitantly with the major morphological transitions, that is, conversion of the oocyte to totipotent 2-cell blastomeres, compaction, and blastocyst formation. Using microarrays, we characterized global changes in gene expression and used Expression Analysis Systematic Explorer (EASE) to identify biological and molecular proces ...[more]

PMID: 15282163

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Preimplantation mouse embryo development MOE430A

Project description:Preimplantation mouse embryo development study on Affymetrix MOE430A. Zeng et al (2004) Dev Biol 272:483-496. Keywords: other

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Project description:Induced pluripotent stem (iPS) cells were produced from reprogramming of somatic cells, and they are shown to possess pluripotent properties similar to embryonic stem (ES) cells. Here we used microarrays to detail the global expression pattern among the ES cells and iPS cells, as well as the original mouse embryo fibroblast (MEF), to identify important players involved in the reprogramming process. Experiment Overall Design: Mouse ES cell cultures, as well as selected iPS cell lines and the original MEF cells they were derived from, were used for RNA extraction and hybridization on Affymetrix microarrays. Three biological replicates for each sample were processed. GeneChips were processed and data were analyzed as previously described (Zeng et al., Dev Biol 20004).

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Mus musculus

Project description:Preimplantation mouse embryo development MOE430A

| PRJNA90611 | ENA

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