Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Russ Carstens
PROVIDER: E-GEOD-17468 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
RNA biology 20091122 5
Cell-type and tissue-specific alternative splicing events are regulated by combinatorial control involving both abundant RNA binding proteins as well as those with more discrete expression and specialized functions. Epithelial Splicing Regulatory Proteins 1 and 2 (ESRP1 and ESRP2) are recently discovered epithelial-specific RNA binding proteins that promote splicing of the epithelial variant of the FGFR2, ENAH, CD44 and CTNND1 transcripts. To catalogue a larger set of splicing events under the r ...[more]