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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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HBX-HepG2 versus Control-HepG2 (no UV)

ABSTRACT: Mature microRNA expression profiling of HBx-expressing HepG2 cells versus Control cells. Free of UV sensitization. The mature microRNA expression profile of HBx-expressing HepG2 cells versus control cells in three independent biological repeated experiments (no UV). This study focuses only on human sequences. The complete data matrix is linked below as a supplementary file.

ORGANISM(S): Homo sapiens

SUBMITTER: Yu Wang

PROVIDER: E-GEOD-17474 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Lethal-7 is down-regulated by the hepatitis B virus x protein and targets signal transducer and activator of transcription 3.

Wang Yu Y Lu Yiwei Y Toh Soo Ting ST Sung Wing-Kin WK Tan Patrick P Chow Pierce P Chung Alexander Y F AY Jooi London L P LL Lee Caroline G L CG

Journal of hepatology 20100402 1

<h4>Background & aims</h4>The pleiotropic hepatitis B virus (HBV) x protein (HBx), associated with hepatocellular carcinoma (HCC), has been implicated in the deregulation of cellular gene expression at the transcriptional level. To date, it remains unknown if HBx regulates the expression of miRNAs which play important roles in gene-regulation at the post-transcriptional and/or translational level.<h4>Methods</h4>miRNA microarrays were employed to compare the expression of cellular miRNAs in HBx- ...[more]

PMID: 20447714

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HBX-HepG2 versus Control-HepG2

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