Transcriptome conservation of the D. discoideum and D. purpureum developmental programs revealed through RNA-sequencing

ABSTRACT: Cross species comparison of genomes and transcriptomes is a powerful tool for understanding underlying biological processes, accurate functional classification of genes, and discovery of novel elements. The shift to next-generation sequencing platforms has tremendously accelerated the analysis of genomes and transcriptomes. The use of this technology for transcriptome analysis has many advantages over hybridization based technologies, including higher sensitivity and specificity, and eliminates the need for probe design. Using Illumina sequencing of mRNAs, we have captured the global transcriptional profiles of the developmental cycles of D. discoideum and D. purpureum. The morphology and transcriptional profiles in these two species have been largely conserved even after greater than 300

ORGANISM(S): Dictyostelium purpureum

SUBMITTER: Anup Parikh 

PROVIDER: E-GEOD-17637 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress