Aerobic transcriptome of Porphyromonas gingivalis
Ontology highlight
ABSTRACT:
ORGANISM(S): Porphyromonas gingivalis
SUBMITTER: Janina Lewis
PROVIDER: E-GEOD-17960 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Adaptation of Porphyromonas gingivalis to microaerophilic conditions involves increased consumption of formate and reduced utilization of lactate.
Lewis Janina P JP Iyer Divya D Anaya-Bergman Cecilia C
Microbiology (Reading, England) 20090814 Pt 11
Porphyromonas gingivalis, previously classified as a strict anaerobe, can grow in the presence of low concentrations of oxygen. Microarray analysis revealed alteration in gene expression in the presence of 6 % oxygen. During the exponential growth phase, 96 genes were upregulated and 79 genes were downregulated 1.4-fold. Genes encoding proteins that play a role in oxidative stress protection were upregulated, including alkyl hydroperoxide reductase (ahpCF), superoxide dismutase (sod) and thiol p ...[more]
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