MicroRNAs show diverse and dynamic expression patterns in multiple tissues of Bombyx mori

ABSTRACT: Background: MicroRNAs (miRNAs) repress target genes at the post-transcriptional level, and function in the development and cell-lineage pathways of host species. Tissue-specific expression of miRNAs is highly relevant to their physiological roles in the corresponding tissues. However, to date, few miRNAs have been spatially identified in the silkworm. Results: We establish for the first time the spatial expression patterns of nearly 100 miRNAs in multiple normal tissues (organs) of Bombyx mori females and males using microarray and Northern-blotting analyses. In total, only 10 miRNAs were universally distributed (including bmo-let-7 and bmo-bantam), while the majority were expressed exclusively or preferentially in specific tissue types (e.g. bmo-miR-275 and bmo-miR-1). We additionally exa

ORGANISM(S): Bombyx mori

SUBMITTER: Zhonghuai Xiang 

PROVIDER: E-GEOD-18039 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress