Recurrent rearrangement during adaptive evolution in an interspecific yeast hybrid suggests a model for rapid introgression

ABSTRACT: Genome rearrangements are associated with eukaryotic evolutionary processes ranging from tumorigenesis to speciation. Such rearrangements are especially common following the shock of interspecific hybridization, and some of these could be expected to have strong selective value. To test this expectation we created de novo interspecific yeast hybrids between two diverged but largely syntenic species, Saccharomyces cerevisiae and S. uvarum, then experimentally evolved them under continuous ammonium limitation. We discovered that a characteristic interspecific genome rearrangement arose multiple times in independently evolved populations. We uncovered nine different breakpoints, all occurring in a ~1 kb region of chromosome 14, and all producing an “interspecific fusion junction” within t

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Barbara Dunn 

PROVIDER: E-GEOD-18060 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress