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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Effects of retinoids on estrogen-receptor-positive and -negative breast carcinoma cells: mRNA profiling

ABSTRACT: The overall study explores differential sensitivity of estrogen-receptor-positive and -negative breast carcinoma cells to retinoids via gene expression and microRNA profiling in MCF7 and MDA-MB-231 cells. This Series reports results of transcriptional profiling of breast carcinoma cell lines comparing the effects of retinoic acid treatment (6 and 48 hours) on estrogen-receptor-positive (MCF7) and estrogen-receptor-negative (MDA-MB-231) cells. mRNA profiling: Retinoic-acid-treated (1microM) vs vehicle-treated cells, two time points (6 and 48h), two cell lines (MCF7 and MDA-MB-231). Two biological replicates for each condition, balanced dye design.

ORGANISM(S): Homo sapiens

SUBMITTER: Maddalena Fratelli

PROVIDER: E-GEOD-18390 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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MicroRNA profiling shows different response to retinoids in estrogen-receptor positive and negative cells

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