Identification of the Early VIP Transriptome and its Associated Interactome in Activated Murine CD4 T Cells

ABSTRACT: Identification of the Early Vasoactive Intestinal Peptide (VIP) Transriptome and its Associated Interactome in Activated Murine CD4 T Cells In an attempt to understand the biological role of this neuropeptide in the immune system, we choose CD4 T cells as a cellular system for identifying a VIP-induced transcriptome. Murine CD4 T cells were isolated and used to identify changes in gene expression in the presence of PMA/ionomycin (activated) for five hours with and without 10-7 M VIP. Balanced-block design, 6 biological replicates. PMA/ionomycin (activated) mouse CD4 T spleenocytes with VIP ligand (sample) vs. PMA/ionomycin (activated) mouse CD4 T spleenocytes without VIP ligand (control), dye-swaps.

ORGANISM(S): Mus musculus

SUBMITTER: Yulia Dementieva 

PROVIDER: E-GEOD-18525 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress