Transcription profiling time series following the recovery of liver samples from Rattus norvegicus subjects after burn injury

ABSTRACT: Animal experiments were performed with male Sprague-Dawley rats (Charles River Laboratories, Boston, MA) weighing 150 ? 200 grams. All experimental protocols used in this study were approved by the Subcommittee on Research Animal Care, Massachusetts General Hospital. Rats were individually housed in a temperature-controlled (25oC) and light-controlled room (12h light-dark cycle) and allowed to adjust to their new surroundings for at least 5 days prior to the experiment. Water and rat chow were provided ad libitum to the animals. On the day of the treatment, the animals were randomly divided into two groups, burned and sham-burned. The burn injury consisted of a full-skin-thickness scald burn of the dorsum, calculated to be ~ 20% of the rat?s total body surface area (TBSA), induced by

ORGANISM(S): Rattus norvegicus

DISEASE(S): burn injury

SUBMITTER: Muralikrishna Vemula 

PROVIDER: E-GEOD-1860 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress