Comparison of gene expression profile between 58 days-old prognatous sea bass jaws and control ones

ABSTRACT: A sea bass oligo microarray platform was used to profile gene expression in mandibles of 58 days-old sea bass affected by prognathism, a skeletal malformation that strongly affects sea bass production. Two different conditions: i) protruding jaws, and ii) normal jaws were used for gene expression analysis. For each condition, total RNA was extracted from four (4) independent biological replicates, each consisting of pools of five (5) jaws. Statistical analysis with SAM (Significance Analysis of Microarray) identified 333 probes (corresponding to 242 unique transcripts) significantly down-regulated in deformed individuals compared to normal ones. In this study, we analyzed eight(8) samples, four (4) pools of jaws dissected from normal sea bass and four (4) pools of jaws dissected from indiv

ORGANISM(S): Dicentrarchus labrax

SUBMITTER: Bargelloni Luca 

PROVIDER: E-GEOD-19001 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress