Dataset Information
Transcription profiling of rat ipsilateral rat hippocampus 3 hr and 24 hr following lateral cortical impact injury and compared to samples from sham-operated controls
Ontology highlight
ABSTRACT:
ORGANISM(S): Rattus norvegicus
SUBMITTER: Eldon Geisert
PROVIDER: E-GEOD-1911 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
High-density microarray analysis of hippocampal gene expression following experimental brain injury.
Journal of neuroscience research 20020301 5
Behavioral, biophysical, and pharmacological studies have implicated the hippocampus in the formation and storage of spatial memory. Traumatic brain injury (TBI) often causes spatial memory deficits, which are thought to arise from the death as well as the dysfunction of hippocampal neurons. Cell death and dysfunction are commonly associated with and often caused by altered expression of specific genes. The identification of the genes involved in these processes, as well as those participating i ...[more]
