Jejunal Peyer’s patch (JPP) gene expression relative to jejunal mesenteric lymph node (j-MLN) gene expression.

ABSTRACT: Although immune mechanisms have been described for Peyer’s patch function, in discriminating food nutrients and commensal microflora from pathogenic challenge, an understanding of gene expression patterns associated with normal intestinal homeostasis is lacking. The effects of commensal bacterial colonization on global gene expression in the small intestine of germ-free mice have been described (1, 2). However, no studies have compared expression patterns of various healthy lymphoid tissues in conventionally-raised pigs or other species. The objective of this study was to investigate the pattern of normal gene expression in jejunal Peyer’s patches (JPP) of healthy pigs. We hypothesized that gene expression of intact jejunal Peyer's patch is characterized by genes associated with absorption

ORGANISM(S): Sus scrofa

SUBMITTER: Kendra Hyland 

PROVIDER: E-GEOD-1913 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress