Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Mary Winn
PROVIDER: E-GEOD-19282 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Winn Mary E ME Zapala Matthew A MA Hovatta Iiris I Risbrough Victoria B VB Lillie Elizabeth E Schork Nicholas J NJ
Mammalian genome : official journal of the International Mammalian Genome Society 20100516 5-6
The use of mouse blood as a model for human blood is often considered in the development of clinically relevant, gene expression-based disease biomarkers. However, the ability to derive biologically meaningful insights from microarray-based gene expression patterns in mouse whole blood, as in human whole blood, is hindered by high levels of globin mRNA. In order to characterize the effects of globin reduction on gene expression of peripheral mouse blood, we performed gene set enrichment analysis ...[more]