Transcription profiling of human primary subcutaneous preadipocytes treated with glucocorticoids prior to the initiation of differentiation

ABSTRACT: Full title: Expression data from human primary subcutaneous preadipocytes treated with glucocorticoids prior to the initiation of differentiation. Preadipocytes are continuously exposed to glucocorticoids in situ due to both steroid present in the circulatory system as well as adipose tissue specific 11βHSD1 activity. While the effects of glucocorticoids during differentiation are well studied, the effect of exposure of preadipocytes to glucocorticoids prior to differentiation is unknown. We therefore treated confluent human primary preadipocytes drived from subcutaneous adipose tissue with the synthetic glucocorticoid dexamethasone for 48 hours prior to the initiation of differentiation and assessed what effect this had on their subsequent potential to differentiate. We found that pre

ORGANISM(S): Homo sapiens

SUBMITTER: Robert Haché 

PROVIDER: E-GEOD-19393 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress