Transcriptome drift of FADU after expression of HIF-1a, Twist1 or Bmi1

ABSTRACT: Expression of HIF-1a or Twist1 or Bmi1 in human hypopharyngeal cancer cell line FADU results in the drift of transcriptome profile from an epithelial cell-like signature to a mesenchymal stem cell-like signature. Stable transfection of pHA-HIF1a(dODD), pFLAG-Twist1 or pcDNA3-Bmi1 in FADU cell and analyzed the transcriptome by cDNA microarray. FADU transfected with pcDNA3.1 empty vector was used as a control of experiment.

ORGANISM(S): Homo sapiens

SUBMITTER: Muh-Hwa Yang 

PROVIDER: E-GEOD-19406 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress