MiRNA profiling by Agilent mouse miRNA microarray

ABSTRACT: miRNAs are 19-25 nucleotides long small RNAs now well-known for their regulatory roles in the development and diseases through post-transcriptional and translational controls in a wide range of species. Mammalian hibernation is a physiological process involving dramatic metabolic suppression and cellular reorganization, during which miRNAs may play an important role. We systematically analyzed the miRNAs in the liver of an extreme hibernating species, arctic ground squirrels (Spermophilus parryii), during two stages of hibernation compared to non-hibernating animals by massively parallel Illumina sequencing technology. We identified more than 200 ground squirrel miRNAs including novel miRNAs specific to ground squirrel and a fast-evolving miRNA cluster that also showed significant differen

ORGANISM(S): Urocitellus parryii

SUBMITTER: Wenchao Hu 

PROVIDER: E-GEOD-19427 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress