Genome-wide mapping of Myc binding site (K562)

ABSTRACT: Proto-oncogene c-myc encodes a bHLH leucine-zipper containing transcription factor which has a DNA binding domain and a transactivation domain. Myc can dimerize with other factors like Max, Mad, Mnt and Miz and can influence transcription of genes. The c-myc oncogene contributes to the genesis of a wide variety of human tumors. A higher than normal level of c-myc gene expression has been observed in 50-80% of colon and breast cancers and a large proportion of human mortality from cancer is caused by abnormal expression of c-myc. For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODEDataReleasePolicyFinal2008.pdf Map binding sites of transcription factor Myc in the genome of K562 cells. The K562 input data

ORGANISM(S): Homo sapiens

SUBMITTER: Michael Wilson 

PROVIDER: E-GEOD-19547 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress