Probiotic-induced differential gene expression during Salmonella challenge in neonatal chicks

ABSTRACT: Salmonella remains an important enteric pathogen of poultry, primarily due to concerns regarding food-borne illness in humans consuming contaminated poultry products. Specific probiotic cultures are efficacious as a treatment for neonatal poultry to prevent enteric infections (competitive exclusion) due to the exquisite susceptibility of young chicks to pathogens in the hatchery and brooding environment. The objective of this experiment was to analyze transcriptional profiles in the ceca of neonatal chicks using the Arizona Gallus gallus 20.7K Oligo Array v1.0, following treatment with a probiotic culture derived from poultry with and without Salmonella enterica subsp. Enteritidis (SE) challenge. Chicks were obtained from a commercial hatchery, and challenged with SE upon arrival at the

ORGANISM(S): Gallus gallus

SUBMITTER: T Porter 

PROVIDER: E-GEOD-19887 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress