The genome of the zebra finch, a songbird

ABSTRACT: This study was part of a larger study on the zebra finch genome (Warren et al 2010. Nature). Here we present a summary of the specific experiment on singing-regulated gene expression. To evaluate the genomic landscape of learned vocal communication, we profiled gene expression in the zebra finch song nucleus, Area X, with custom Agilent oligoarrays for up to seven hours following initiation of singing. We developed algorithms to identify singing-regulated transcripts related to time spent singing, and discovered over 800 transcripts in Area X that are significantly regulated by singing. These included known increases of the egr1 and c-fos transcription factors, and a decrease in the FoxP2 transcription factor, a gene associated with spoken language development. We clusted the singing-regul

ORGANISM(S): Taeniopygia guttata

SUBMITTER: Saurabh Sinha 

PROVIDER: E-GEOD-19900 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress