Transcription profiling of chromophobe renal cell carcinoma and oncocytoma samples

ABSTRACT: [original title] Genomic expression and single-nucleotide polymorphism profiling discriminates chromophobe renal cell carcinoma and oncocytoma. Background : Chromophobe renal cell carcinoma (chRCC) and renal oncocytoma are two distinct but closely related entities with strong morphologic and genetic similarities. While chRCC is a malignant tumor, oncocytoma is usually regarded as a benign entity. The overlapping characteristics are best explained by a common cellular origin, and the biologic differences between chRCC and oncocytoma are therefore of considerable interest in terms of carcinogenesis, diagnosis and clinical management. Previous studies have been relatively limited in terms of examining the differences between oncocytoma and chromophobe RCC. Methods : Gene expression profili

ORGANISM(S): Homo sapiens

SUBMITTER: Min Tan 

PROVIDER: E-GEOD-19982 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress