RAW264.7 gene expression after exposure to 1-50ug/ml AF-SWCNT-24 hours

ABSTRACT: Single-walled carbon nanotubes (SWCNTs) are being explored and used for a wide range of applications in industrial and medical sectors, and the increasing exposure of SWCNTs necessitate the studies of their potential environmental and health effects. Considerable efforts have been made to improve the dispersion of SWCNTs by chemical modifications. The present study was designed to determine if the acid functionalization of SWCNTs enhanced the toxicity and more efforts were made to understand the molecular mechanisms. RAW264.7 cells were exposed to 0-100μg/mL of SWCNTs and AF-SWCNTs for 24 hours and cell proliferation, viability, and gene expression profiles were assessed and compared. Results showed that the magnitude of AF-SWCNT-induced cell proliferation inhibition was higher than that o

ORGANISM(S): Mus musculus

SUBMITTER: Bin Wan 

PROVIDER: E-GEOD-20021 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress