Sex bias and dosage compensation in the zebra finch versus chicken genomes: general and specialized patterns among birds

ABSTRACT: We have performed a comparison of global patterns of gene expression between two bird species, the chicken and zebra finch, especially with regard to sex bias of autosomal vs. Z chromosome genes, dosage compensation and evolution of sex bias. Both species appear to lack a Z chromosome-wide mechanism of dosage compensation, because both have a similar pattern of significantly higher expression of Z genes in males relative to females. Unlike the chicken Z chromosome, which has female-specific expression of the non-coding RNA MHM (male hypermethylated), and acetylation of histone 4 lysine 16 (H4K16) near MHM, the zebra finch Z chromosome appears to lack the MHM sequence and acetylation of H4K16. The zebra finch also does not show the reduced male to female (M:F) ratio of gene expression near

ORGANISM(S): Taeniopygia guttata

SUBMITTER: Juli Wade 

PROVIDER: E-GEOD-20035 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress