Global responses of Aliivibrio salmonicida to hydrogen peroxide

ABSTRACT: Aliivibrio salmonicida causes “cold-water vibriosis” (or “Hitra disease”) in fish, including marine-reared Atlantic salmon. During development of the disease the bacterium will encounter macrophages with antibacterial activities such as production of damaging reactive oxygen species (ROS). To defend itself the bacterium will presumably start producing detoxifying enzymes, reducing agents, and proteins involved in DNA and protein repair systems. Even though responses to oxidative stress are well studied for a few model bacteria, little work has been done in general to explain how important groups of pathogens, like members of the Vibrionaceae family, can survive at high levels of ROS. We have used bioinformatic tools and an –omics approach to study how A. salmonicida responds to h

ORGANISM(S): Aliivibrio salmonicida LFI1238

SUBMITTER: Peik Haugen 

PROVIDER: E-GEOD-20082 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress